abstract：BACKGROUND:α-glucosidase inhibitors regulate postprandial hyperglycemia (PPHG) by impeding the rate of carbohydrate digestion in the small intestine and thereby hampering the diet associated acute glucose excursion. PPHG is a major risk factor for diabetic vascular complications leading to disabilities and mortality in...

journal_title：Nutrition & metabolism

authors： Mohamed Sham Shihabudeen H,Hansi Priscilla D,Thirumurugan K

更新日期：2011-06-29 00:00:00

abstract：BACKGROUND:Adipocyte volume (fat accumulation) and cell number (adipogenesis) is increased in obese individuals. Our objective was the identification of dietary constituents with inhibitory effects on triglyceride formation during adipogenesis. Therefore an in vitro adipose cell assay in murine C3H10 T1/2 cells was dev...

journal_title：Nutrition & metabolism

authors： Warnke I,Goralczyk R,Fuhrer E,Schwager J

更新日期：2011-05-12 00:00:00

abstract：BACKGROUND:Reducing dietary energy density has proven to be an effective strategy to reduce energy intakes and promote weight control. This effect appears most robust when a low energy dense preload is consumed before meals. Yet, much discussion continues regarding the optimal form of a preload. The purpose of the pres...

journal_title：Nutrition & metabolism

authors： Silver HJ,Dietrich MS,Niswender KD

更新日期：2011-02-02 00:00:00

abstract：: This paper reviews evidence in the context of current research linking dietary fructose to health risk markers.Fructose intake has recently received considerable media attention, most of which has been negative. The assertion has been that dietary fructose is less satiating and more lipogenic than other sugars. Howev...

journal_title：Nutrition & metabolism

authors： Rizkalla SW

更新日期：2010-11-04 00:00:00

abstract：BACKGROUND:Dihydrocapsiate (DCT) is a natural safe food ingredient which is structurally related to capsaicin from chili pepper and is found in the non-pungent pepper strain, CH-19 Sweet. It has been shown to elicit the thermogenic effects of capsaicin but without its gastrointestinal side effects. METHODS:The present...

journal_title：Nutrition & metabolism

authors： Lee TA,Li Z,Zerlin A,Heber D

更新日期：2010-10-06 00:00:00

abstract：: Dietary ratios of omega-3 (n-3) to omega-6 (n-6) polyunsaturated fatty acids (PUFAs) have been implicated in controlling markers of the metabolic syndrome, including insulin sensitivity, inflammation, lipid profiles and adiposity. However, the role of dietary PUFAs in regulating energy systems in healthy relative to ...

journal_title：Nutrition & metabolism

authors： Burghardt PR,Kemmerer ES,Buck BJ,Osetek AJ,Yan C,Koch LG,Britton SL,Evans SJ

更新日期：2010-06-28 00:00:00

abstract：BACKGROUND:Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We re...

journal_title：Nutrition & metabolism

authors： Zuccoli G,Marcello N,Pisanello A,Servadei F,Vaccaro S,Mukherjee P,Seyfried TN

更新日期：2010-04-22 00:00:00

abstract：: Liver steatosis is a frequent histological feature in patients chronically infected with hepatitis C virus (HCV). The relationship between HCV and hepatic steatosis seems to be the result of both epigenetic and genetic factors. In vivo and in vitro studies have shown that HCV can alter intrahepatic lipid metabolism b...

journal_title：Nutrition & metabolism

authors： Mirandola S,Bowman D,Hussain MM,Alberti A

更新日期：2010-02-23 00:00:00

abstract：BACKGROUND:The composition of dietary fatty acids (FA) during early life may impact adult adipose tissue (AT) development. We investigated the effects of alpha-linolenic acid (ALA) intake during the suckling/weaning period on AT development and metabolic markers in the guinea pig (GP). METHODS:Newborn GP were fed a 27...

journal_title：Nutrition & metabolism

authors： Pouteau E,Aprikian O,Grenot C,Reynaud D,Pace-Asciak C,Cuilleron CY,Castañeda-Gutiérrez E,Moulin J,Pescia G,Beysen C,Turner S,Macé K

更新日期：2010-01-29 00:00:00

abstract：:Breast cancer is the most prevalent cancer in American women. Dietary factors are thought to have a strong influence on breast cancer incidence. This study utilized a meal-feeding protocol with female Sprague-Dawley rats to evaluate effects of two ratios of carbohydrate:protein on promotion and early progression of br...

journal_title：Nutrition & metabolism

authors： Moulton CJ,Valentine RJ,Layman DK,Devkota S,Singletary KW,Wallig MA,Donovan SM

更新日期：2010-01-10 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the relationship between intakes of energy-providing macronutrients, and markers of cardio metabolic risk factors in high BMI African American (AA) children. METHODS:A cross sectional analysis of a sample of 9-11 year old children (n = 80) with BMI greater then the 85th...

journal_title：Nutrition & metabolism

authors： Sharma S,Roberts LS,Hudes ML,Lustig RH,Fleming SE

更新日期：2009-10-13 00:00:00

abstract：BACKGROUND:Many publications link high homocysteine levels to cardiovascular disease. In Spain there is little information on the prevalence of hyperhomocysteinaemia and associated vitamin factors among the general population, and less still among children. Cardiovascular risk factors in the childhood population may be...

journal_title：Nutrition & metabolism

authors： Gil-Prieto R,Hernández V,Cano B,Oya M,Gil A

更新日期：2009-10-05 00:00:00

abstract：BACKGROUND:Dietary n-3-polyunsaturated fatty acids (n-3-PUFA) have been shown to reduce body weight and fat mass in rodents as well as in humans in one small short-term study. We conducted this controlled randomized dietary trial to test the hypothesis that n-3-PUFA lower body weight and fat mass by reducing appetite a...

journal_title：Nutrition & metabolism

authors： Kratz M,Callahan HS,Yang PY,Matthys CC,Weigle DS

更新日期：2009-05-29 00:00:00

abstract：BACKGROUND:The conjugated linoleic acid (CLA) content of beef can be increased by supplementing appropriate beef cattle diets with vegetable oil or oil seed. Yet the effect of consumption of such beef on adipose tissue characteristics is unclear, thus the study was conducted to compare adipose tissue responses of rats ...

journal_title：Nutrition & metabolism

authors： He ML,Mir PS,Okine EK,Napadajlo H

更新日期：2009-04-22 00:00:00

abstract：BACKGROUND:Endothelial dysfunction (ED) is an independent predictor of cardiovascular events. ED is also a reversible disorder, and nitric oxide donors like L-arginine may promote this process. Despite the positive results from several studies, there are some studies that have shown that L-arginine administration did n...

journal_title：Nutrition & metabolism

authors： Javanmard SH,Nematbakhsh M,Sanei MH

更新日期：2009-03-24 00:00:00

abstract：: Drug-drug interactions have become an important issue in health care. It is now realized that many drug-drug interactions can be explained by alterations in the metabolic enzymes that are present in the liver and other extra-hepatic tissues. Many of the major pharmacokinetic interactions between drugs are due to hepa...

journal_title：Nutrition & metabolism

authors： Bibi Z

更新日期：2008-10-18 00:00:00

abstract：BACKGROUND:Body volume expands with the positive energy balance associated with the development of adult human obesity and this "growth" is captured by two widely used clinical metrics, waist circumference and body mass index (BMI). Empirical correlations between circumferences, BMI, and related body compartments are f...

journal_title：Nutrition & metabolism

authors： Heymsfield SB,Martin-Nguyen A,Fong TM,Gallagher D,Pietrobelli A

更新日期：2008-10-06 00:00:00

abstract：: Prior to the discovery of medical treatment for diabetes, carbohydrate-restriction was the predominant treatment recommendation to treat diabetes mellitus. In this commentary we argue that carbohydrate-restriction should be reincorporated into contemporary treatment studies for diabetes mellitus. ...

journal_title：Nutrition & metabolism

authors： Westman EC,Vernon MC

更新日期：2008-04-09 00:00:00

abstract：BACKGROUND:Total body water (TBW) estimations have been used to estimate body composition, particularly fat-free mass, to aid in nutritional interventions, and to monitor hydration status. In the past, bioimpedance spectroscopy (BIS) devices have been used to estimate TBW. Previous investigations have examined the vali...

journal_title：Nutrition & metabolism

authors： Moon JR,Tobkin SE,Roberts MD,Dalbo VJ,Kerksick CM,Bemben MG,Cramer JT,Stout JR

更新日期：2008-03-19 00:00:00

abstract：BACKGROUND:To study the effects of a pre-germinated brown rice diet (PR) on diabetic neuropathy in streptozotocin (STZ)-induced diabetic rats. METHODS:The effects of a PR diet on diabetic neuropathy in STZ-induced diabetic rats were evaluated and compared with those fed brown rice (BR) or white rice (WR) diets with re...

journal_title：Nutrition & metabolism

authors： Usuki S,Ito Y,Morikawa K,Kise M,Ariga T,Rivner M,Yu RK

更新日期：2007-11-23 00:00:00

abstract：BACKGROUND:A major portion of available fatty acids for adipocyte uptake is derived from lipoprotein lipase (LPL)-mediated hydrolysis of circulating lipoprotein particles. In vivo studies aimed at identifying the precise role of adipocyte-derived LPL in fat storage function of adipose tissue have been unable to provide...

journal_title：Nutrition & metabolism

authors： Gonzales AM,Orlando RA

更新日期：2007-10-30 00:00:00

abstract：PURPOSE:To determine the influence of menstrual irregularity, oral contraceptive use and other factors on bone mineral density (BMD) and bone size at different skeletal sites in 135 college-aged fit women. METHODS:Menstrual history, oral contraceptive use, exercise history, and nutritional factors including calcium, c...

journal_title：Nutrition & metabolism

authors： Ruffing JA,Nieves JW,Zion M,Tendy S,Garrett P,Lindsay R,Cosman F

更新日期：2007-08-06 00:00:00

abstract：:There has been intense interest in defining the functions of UCP2 and UCP3 during the nine years since the cloning of these UCP1 homologues. Current data suggest that both UCP2 and UCP3 proteins share some features with UCP1, such as the ability to reduce mitochondrial membrane potential, but they also have distinctly...

journal_title：Nutrition & metabolism

authors： Fisler JS,Warden CH

更新日期：2006-09-12 00:00:00

abstract：:We studied the regulation of brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and insulin. Mice were deprived of food and water for time periods of 1, 3, 6, 9, 12 and 24 hours and were then allowed to re-feed for 5, 30 and 60 minut...

journal_title：Nutrition & metabolism

authors： Karami KJ,Coppola J,Krishnamurthy K,Llanos DJ,Mukherjee A,Venkatachalam KV

更新日期：2006-02-16 00:00:00

abstract：BACKGROUND:Sub-optimally nourished rats show reduced growth, biochemical and physiological changes. However, no one has assessed metabolic rate adaptations in rats subjected to chronic suboptimal nutrition (CSN). In this study energy expenditure (EE; kcal/100 g body weight) and physical activity (PA; oscillations in we...

journal_title：Nutrition & metabolism

authors： Rising R,Lifshitz F

更新日期：2006-01-31 00:00:00

abstract：BACKGROUND:Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. Currently, no method allows simple, direct quantification of holotranscobalamin. We now report on the identificat...

journal_title：Nutrition & metabolism

authors： Orning L,Rian A,Campbell A,Brady J,Fedosov SN,Bramlage B,Thompson K,Quadros EV

更新日期：2006-01-04 00:00:00

abstract：:Although feeding deficits have been reported in snakes and lizards following vomeronasal system disruption, no deficit has been previously reported in a mammal. We tested gray short-tailed opossums with items from four different food categories prior to occluding access to the vomeronasal organ. Preoperatively, opossu...

journal_title：Nutrition & metabolism

authors： Halpern M,Daniels Y,Zuri I

更新日期：2005-02-22 00:00:00

abstract：:Glucocorticoids are stress hormones that modulate a large number of physiological actions involved in metabolic, inflammatory, cardiovascular and behavioral processes. The molecular mechanisms and the physiological effects of glucocorticoids have been extensively studied. However, the involvement of glucocorticoid act...

journal_title：Nutrition & metabolism

authors： Wang M

更新日期：2005-02-02 00:00:00

abstract：:OBJECTIVE: To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in overweight/obese men and women. DESIGN: Randomized, balanced, two diet period clinical intervention ...

journal_title：Nutrition & metabolism

authors： Volek J,Sharman M,Gómez A,Judelson D,Rubin M,Watson G,Sokmen B,Silvestre R,French D,Kraemer W

更新日期：2004-11-08 00:00:00